title.gif (5682 bytes)

Selected Publications

R.D.Katsarava, D.P.Kharadze, L.M.Avalishvili, M.M.Zaalishvili
Synthesis of polyamides from bis-pentafluorophenyl esters of dicarbonic acids and diamines.
Makromol.Chem. Rapid Comm. 5,585 (1984)

R.D.Katsarava, D.P.Kharadze, N.Sh.Japaridze, L.M.Avalishvili, T.N.Omiadze, M.M.Zaalishvili
Heterochain polymers based on natural amino acids. Synthesis of polyamides on the base of N?,N??- bis-trimethylsilyl lysine alkyl esters.
Makromol.Chem. 186,939 (1985)

R.D.Katsarava, D.P.Kharadze, L.M.Avalishvili,
Synthesis of high-molecular-weight polysuccinamides by polycondesation of active succinates with diamines.
Makromol.Chem. 187, 2053 (1986)

R.D.Katsarava, D.P.Kharadze, L.Kirmelashvili, N.Medzmariashvili, Ts.Goguadze, G.Tsitlanadze.
Polyamides from 2,2’-p-phenilene-bis(?2-5-oxazoline)s and N,N’-bistrimethylsilylated diamines. Synthesis of polyamides containing dipeptide links in the main chains.
Makromol.Chem. 194, 143 (1993)

R.D.Katsarava, D.P.Kharadze, L.I. Kirmelashvili, M.M.Zaalishvili
Heterochain polymers based on natural ?-amino acids. Bis-oxazolinone method of the synthesis of polyamides containing enzymatically cleavable bonds in the main chains.
Acta Polymerica, 36,29 (1985)

R.D.Katsarava, D.P.Kharadze, T.M.Bendiashvili, Ya.G.Urman, I.Ya.Slonim, S.G.Alekseeva, P.Cefelin, V.Janout
Synthesis of polyamides by active polycondensation. The structural and kinetical aspects of active esters aminolysis reactions.
Acta Polymerica, 39,523 (1988)

R.D.Katsarava, D.P.Kharadze, P.L.Toidze, T.N.Omiadze, N.N.Japaridze, M.K.Pirskalava.
Some physicochemical properties of biocompatible and biodegradable heerochain polymers based on L-lysine ethyl ester.
Acta Polymerica, 42,95 (1991)

R.D.Katsarava, G.I.Timofeeva, P.L.Toidze, Yu.A.Davidovich, Yu.A.Lavrukhin, S.A.Pavlova, E.I.Fedin, M.M.Zaalishvili.
Heterochain polymers based on natural ?-amino acids. On microstructure of polyurea based on L-lysine.
Vysokomol. Soed. Ser. B. 27,483 (1985)

R.D.Katsarava, T.M.Kartvelishvili
A new method of the synthesis of polyurethanes by interaction of diol bis-chloroformates with N,N’-bis-trimethylsilylated diamines.
Vysokomol. Soed. Ser. B. 28,377 (1986)

R.D.Katsarava, D.P.Kharadze, L.M.Avalishvili
Synthesis of polyamides based on aspartic and glutamic acids.

Vysokomol. Soed. Ser. B. 27,518 (1986)

R.D.Katsarava, T.M. Kartvelishvili, D.P.Kharadze, M.M.Zaalishvili, M.M.Patsuria.
Synthesis of polyurethanes by polycondesation of active bis-carbonates of diols with diamines under mild conditions.
Vysokomol. Soed. Ser. A. 29,2069 (1987)

R.D.Katsarava
Synthesis of heterochain polymers using chemically activated monomers (Active Polycondesation). Review.
Vysokomol. Soed. Ser. A. 31,1555 (1989)

N.G.Medzmariashvili, L.I.Kirmelashvili, D.P.Kharadze, Ts.A.Goguadze R.D.Katsarava,
Synthesis of novel polyanhydrides.
Vysokomol. Soed. Ser. B. 34,3(1992)

R.D.Katsarava, T.M. Kartvelishvili, Yu.A.Davidovich, M.M.Zaalishvili, S.V.Rogozhin.
A new method of the synthesis of polyureas by the interaction of active diphenylcarbonates with diamines and their trimethylsilylated derivatives.
Dokl. Akad. Nauk SSSR, 266, 363 (1982)

R.D.Katsarava, T.M. Kartvelishvili, M.M.Zaalishvili.
Heterochain polymers based on natural amino acids. Synthesis of novel, optically active polyurethanes by interaction of N?,N?-bis-carbonyl-L-lisine ethyl ester with diols.
Dokl. Akad. Nauk SSSR, 281, 591 (1985)

16. A.V.Maksimenko, L.A.Nadirashvili,V.V.Abramova, G.S.Erkomaishvili, R.D.Katsarava, V.P.Torchilin
Modification of the Papaia proteinase complex with synthetic polymers. Study of degradation of the enzyme preparation.
Biotekhnologia (USSR), 1, 29 (1990)

I.K.Svanidze, R.D.Katsarava, E,V.Didimova
The use of polymeric fibres as substrates for cultivation of nerve tissue.
Cytologia (USSR), 29, 611 (1987).

R.D.Katsarava
Condensing agents in polycondensation.
Uspekhi Khimii (Russian Chem.Rev), 58, 1549 (1989).

R.D.Katsarava
Advances and problems of active polycondensation.
Uspekhi Khimii (Russian Chem.Rev), 60, 1419 (1991).

R.D.Katsarava, D.P.Kharade
Heterocyclic bifunctional monomers in polymer synthesis.
Uspekhi Khimii (Russian Chem.Rev), 61, 161 (1992).

R.D.Katsarava, Ya.S.Vygodski
Silylation in the chemistry of polymers.
Uspekhi Khimii (Russian Chem.Rev), 61, 1142 (1992)

R.D.Katsarava, Ya.S.Vygodski
Silylation in the chemistry of polymers.
Polymer Yearbook. Harwood Publish. – London, v.11, p.193-228 (1994).

R.D.Katsarava, T.M.Kartvelishvili, N.N.Japaridze, Ts.A.Goguadze, T.A.Khosruashvili, R.P.Tiger, P.A.Berlin.
Synthesis of polyureas by polycondensation of diamines with active derivatives of carbonic acid.
Makromol. Chem., 194,3209 (1993)

N.Arabuli, G.Tsitlanadze, L.Edilashvili., D..Kharadze, Ts.Goguadze, V.Beridze, Z.Gomurashvili, R..Katsarava
Heterochain polymers based on natural ?-amino acids. Synthesis and enzymatic hydrolysis of regular poly(ester amide)s based on bis(L-phenylalanine) ??? – alkyne diesters and adipic acid.
Makromol. Chem. Phys., 195,2279 (1994)

R.Katsarava, T.Kartvelishvili, T.Khosruashvili, V.Beridze
Synthesis of polyurethanes by polycondesation of active bis-carbonates of diols with hexamethylene diamine and its derivatives.
Makromol. Chem. Phys., 196,3061 (1995)

T.Kartvelishvili, A.Kvintradze, R.Katsarava
Amino acid based bioanalogous polymers. Synthesis of novel poly(urethane amide)s based on N,N-(trimethylenedioxydicarbonyl)-bis-(phenylalanine).
Makromol. Chem. Phys., 197,249 (1996).

T.Kartvelishvili, G.Tsitlanadze, L.Edilashvili, R.Katsarava
Amino acid based bioanalogous polymers. Regular poly(ester urethane)s and poly(ester urea)s based on bis(phenylalanine) ??? – alkyne diesters.
Makromol. Chem. Phys., 198,1921 (1997).

H.R.Kricheldorf, V.Linzer, R.Katsarava
New polymer synthesis. Polyamides with non-cyclic imide groups by acylation of N,N’-bis-trimethylsilylamines.
New Polymeric Materials, 5, 35 (1996)

R.Katsarava, V.Beridze, N.Arabuli, D.Kharadze, C.C.Chu, C.Y.Won.
Amino acid based bioanalogous polymers. Synthesis and study of regular poly(ester amide)s based on bis(?-amino acid) ????– alkylene diesters and aliphatic dicarboxylic acids.
J.Polym.Sci.: Part A:Polym.Chem. 37, P.391 (1999).

D.Kharadze, L.Kirmelashvili, N.Medzmariashvili, V.beridze. G.Tsitlanadze, D.Tughushi, C.C.Chu, R.Katsarava
Synthesis and a-chymotrypsinolysis of regular poly(ester amides)s based on phenylalanine, diols and terephthalic acid.
Polymer Sci. (Russia), Ser.A., 41, P.883 (1999)

Z.Gomurashvili, H.R.Kricheldorf, R.Katsarava
Amino acid based bioanalogous polymers. Synthesis and study of new regular poly(ester amides)s composed of hydrophobic ?-amino acids and dianhydrohexitoles.
J.Macromol. Sci.-Pure and Appl. Chem. 37(3), 215 (2000)

C.C.Chu, R. Katsarava
Elastomeric functional biodegradable copolyester amides and copolyester urethanes.
U.S. Patent 6,503,538 B1 (2003).

R. Katsarava, Z. Alavidze
Polymeric blends as biodegradable matrices for preparing biocomposites,
US Patent Application # 09/757,704.

K. Markoishvili, G. Tsitlanadze, R. Katsarava, J.G. Morris,. A. Sulakvelidze,
A Novel Sustained-Release Matrix Based on Biodegradable Poly(Ester Amide)s and Impregnated with Bacterio-phages and an Antibiotic Shows Promise in Healing Wounds Infected with Various Pathogenic Bacteria,
Intern.J.Dermatology , 41, 453 (2002).

S.H. Lee, I. Szinai, K.Carpenter, R. Katsarava, G. Jokhadze, C.C.Chu, Y. Huang, E.Verbeken, O.Bramwell, I. De Scheerder, M.K. Hong.
In Vivo Biocompatibility Evaluation of Stents Coated With A New Biodegradable Elastomeric and Functional Polymer.
Coronary Artery Disease, 13 (4), 237-241 (2002).

R.Katsarava
Active Polycondensation – from peptide chemistry to amino acid based biodegradable polymers,
In: H.R.Kricheldorf (Ed.), “Polycondensation 2002”, Macromolecular Symposia,
199, P. 419-429, Wiley-VCH, September, 2003.G.Tsitlanadze,

M.Machaidze, T.Kviria, N.Djavakhishvili, C.C.Chu, R.Katsarava.
Biodegradation of amino acid based poly(ester amide)s: in vitro weight loss and preliminary in vivo studies.
J. Biomater. Sci., Polym. Ed., 15 (4), 1-24 (2004).

G.Tsitlanadze, T.Kviria, C.C.Chu, R.Katsarava.
Biodegradation of amino acid based poly(ester amide)s: in vitro study using potentiometric titration.
J Mater Sci.: Mater in Medicine (in press).

Kebadze N., Kviria T., Edilashvili L., Omiadze T., Tsitlanadze G, Kandelaki K., Gorgiladze G, Katsarava R.,
The preparation of porous films based on biodegradable poly(ester-amide),
Proccedings Georg.Acad.Sci., Ser.Biol. (in press).

Guo K., Chu C. C., Chkhaidze E., Katsarava R., Synthesis and Characterization of Novel Biodegradable Unsaturated Poly(Ester-Amide)s,
J. Polym. Sci. Part A: Polym. Chem. 43, 1463-1477 (2005).

D. Jikia, N. Chkhaidze, E. Imedashvili, I. Mgaloblishvili, G.Tsitlanadze, R.Katsarava, J.Glenn Morris, Jr., A.Sulakvelidze, The use of PhagoBioDerm, a novel biodegradable preparation capable of the sustained release of bacteriophages and ciprofloxacin, in the complex treatment of Staphylococcus aureus-infected local radiation injuries caused by the exposure to Sr90,
Clinical and Experimental Dermatology, 30, 23-26 (2005).

N.Neparidze, M.Machaidze, N.Zavradashvili, N.Mazanashvili, V.Tabidze, D.Tugushi, R.Katsarava, Biodegradable copoly(ester amide)s with hydrophobic lateral substituents.
Polimery i Meditsina, Russia, #2, 27-33 (2006).

R.Katsarava, G.Jokhadze, N.Neparidze, N.Zavradashvili, E.Chkhaidze, Non-traditional macromolecular systems composed of ?-amino acids,
Proceedings of the International Conference “New Polymer Systems for Biotechnological and Biomedical Applications”, 12-14 July, Yerevan, Armenia, 2005, PP. 66-74.

M.Samkharadze, D.Tugushi, G.Gverdtsiteli, G.Otinashvili, N.Basharuli, N.Neparidze, R.Katsarava, Synthesis and study of biodegradable functional poly(ester urethane)s with lateral carboxyl groups,
Proceedings of the International Conference“New Polymer Systems for
Biotechnological and Biomedical Applications”, 12-14 July,Yerevan, Armenia, 2005, PP.140-145.

V.Tabidze, P.Toidze, M.Machaidze, R.Katsarava, In vitro biodegradation of a-amino
acid based poly(ester amide)s: Further evidence for erosive mechanism
,
Proceedings of the International Conference “New Polymer Systems for Biotechnological and Biomedical Applications”, 12-14 July,Yerevan, Armenia, 2005, PP. 172-175.

R.Katsarava, Z. Gomurashvili, E. Chkhaidze, N. Mazanashvili, N. Mchedlishvili,
N.Zavradashvili, D.Tugushi, M. Gverdtsiteli, New, amino acid based unsaturatedbiodegradable poly(ester amide)s with double bond moieties in the backbones. Proceedings of the
International symposium “Polycondensation-2006”, 27-30 August, 2006, Istanbul, Turkey, PP. 54-55.

Z.Gomurashvili, H.Zhang, T.D.Jankins, J.Huges, M.Wu, L.Lambert, L.Eltepu, C.Pabba, N.Chowdari, V.Vasilev, R.Katsarava, B.Turnell, From drug-eluting stents to bio-pharmaceuticals: Poly(ester amide) a versatile new bioabsorbable polymer.
ACS 232nd National Meeting, 10-14 September, 2006, San Francisco, CA.

G.Jokhadze, M.Machaidze, H. Panosyan, C.C.Chu, R.Katsarava, Synthesis and characterization of functional elastomeric poly(ester amide)s copolymers.
J. Biomater. Sci. Polym. Ed., 18(4), 411-438 (2007).

R.Katsarava, T.Kviria, E.Chkhaidze, N.Zavradashvili, G.Jokhadze, Enzyme catalyzed in vitro hydrolysis (biodegradation) study of ?-amino acid based non-conventional macromolecular substrates.
Plant & Microbial Enzymes: Isolation, Characterization & Biotechnology Application.
Intern workshop, Tbilisi, 2-5 July, 2007. Proceedings, p. 8-11.

I. Legashvili, N. Nepharidze, R. Katsarava, B. Sannigrahi, I.M. Khan, Non-covalent nano-adducts of co-poly(ester amide) and poly(ethylene glycol): preparation, characterization and model drug-release studies.
J. Biomater. Sci. Polymer Edn, Vol. 18, No. 6, pp. 673–685 (2007).

R. Katsarava, D.Tugushi, N. Zavradashvili, Z.Gomurashvili, G. Jokhadze, M. Gverdtsiteli, M. Samkharadze, Amino Acid Based Epoxy-Poly(Ester Amide)s – a New Class of Biodegradable Functional Polymers: Synthesis and Characterization.
Polymers in Medicine and Biology, Santa Rosa, CA, 2007.

D. Tugushi, M.Samkharadze, M. Gverdtsiteli, G.Otinashvili, M.Bedinashvili, N. Basharuli, V.Tabidze, P. Toidze, M.Machaidze, R.Katsarava, Amino Acid Based Poly(ether ester urethane)s – a New Class of Biodegradable Polymers,
Polymers in Medicine and Biology, Santa Rosa, CA, 2007.

R. Katsarava, G.Tsitlanadze, N.Kebadze, N.Nadirashvili, G.Jokhadze, D.Tugushi, Z.Gomurashvili, H.Zhang, J. Da, J. Hughes, M. Wu, M.Barrozo, D.Martinez, K. M. DeFife, W.G. Turnell, Amino acid based biodegradable poly(ester amide)s - promising wound dressing and stent coating materials,
International Symposium “New Polymers and Radioprotectors for Biology and
Medicine”, Yerevan, Armenia, October 8-10, 2007.

V. Tabidze, T. Memanishvili, N. Kebadze, R. Katsarava, DSC study of drug eluting system composed of biodegradable poly(ester amide)s and a model drug.
International Symposium “New Polymers and Radioprotectors for Biology and
Medicine”, Yerevan, Armenia, October 8-10, 2007.

N. Ochkhikidze, E. Razmadze , D. Tugushi, N. Kupatadze, Z. Gomurashvili, R.Katsarava, AABB-poly(depsipeptide)s – a new class of amino acid based biodegradable polymers.
International symposium “Polycondensation-2008”, 8-11 September, 2008, Tokyo, Japan.

N.Zavradashvili, G.Jokhadze, T.Kviria, R.Katsarava, Thermally- and photo-chemically curable biodegradable poly(ester amide)s with double bond moieties in lateral chains,
In: Chemistry of Advanced Compoiunds and Materials, N.Lekishvili and G.E.Zaikov, Eds. NOVA Science Publishers, Inc., PP 173-179 (2008).

R.Katsarava, D.Kharadze, D.Tugushi, New biodegradable polymers composed of naturally occurring ?-amino acids. Polychar-17, April 20-24, 2009, Ruen, France.

D. Tugushi, N. Zavradashvili, Z. Gomurashvili, G. Jokhadze, M. Gverdtsiteli,N. Kupatadze,
R. Katsarava, Biodegradable epoxy-poly(ester amide)s – a new class of chemo- and
thermoreactive polymers for numerous biomedical applications, Polychar-17, April 20-24, 2009, Ruen, France.

T. Memanishvili, N. Kupatadze, D. Tugushi, V.P. Torchilin, R. Katsarava, Biodegradable arginine-based polymers with PEG-like backbones as potential non-viral gene delivery system, 1st Russian-Hellenic Symposium with International Participation and Yong’s Scientist School “Biomaterials and bionanomaterials: recent advances and safety-toxicology issues”, May 3-9, 2010, Iraklion, Crete, Greece.


Copyright Research Center for Medical Polymers and Biomaterials, 1993-2010
All Rights Reserved